How immunosuppressed are you?The duration and intensity of immunosuppression determine risks. Short-term immunosuppression from IRTs is front-loaded and don't accumulate with time,…
| 35 | 34 | Share this post How immunosuppressed are you? gavingiovannoni.substack.com |
Case study: how do you define a rituximab failure?This patient with MS is anxious that he may have early secondary progressive MS and rituximab is failing him. He is keen to explore AHSCT. Is this appr…
| 6 | 12 | Share this post Case study: how do you define a rituximab failure? gavingiovannoni.substack.com |
It was the worst pain I have ever hadTrigeminal neuralgia, brief, very painful, electric shock-like episodes in the distribution of the trigeminal nerve is common in people with MS. This n…
| 33 | 29 | Share this post It was the worst pain I have ever had gavingiovannoni.substack.com |
Case study: Ocrelizumab and the timing of the 3rd dose of the vaccine?I am getting endless questions about when is the best time to have the 3rd and/or booster dose of the COVID-19 vaccine in relation to ocrelizumab infus…
| 39 | 53 | Share this post Case study: Ocrelizumab and the timing of the 3rd dose of the vaccine? gavingiovannoni.substack.com |
How do I want my MS to be treated?The newsletter addresses the differences between maintenance-escalation disease-modifying therapies and immune reconstitution therapies (IRTs) and why …
| 40 | 38 | Share this post How do I want my MS to be treated? gavingiovannoni.substack.com |
Case study: a patronizing neurologistWhen a neurologist thinks alemtuzumab is too risky the question needs to be asked ‘too risky for whom; the neurologist or the patient?’.
| 10 | 12 | Share this post Case study: a patronizing neurologist gavingiovannoni.substack.com |
What are your priorities in relation to 'Your MS'?Many readers of these Newsletters are highlighting that they haven’t seen their neurologist or a neurologist, for some time now. Many of you sta…
| 65 | 14 | Share this post What are your priorities in relation to 'Your MS'? gavingiovannoni.substack.com |
Case study: are you a zombie because of your spasticity medications?Are you battling to get your nocturnal spasms under control? Are your legs collapsing when you increase the dose of your anti-spastic medication?
| 7 | 5 | Share this post Case study: are you a zombie because of your spasticity medications? gavingiovannoni.substack.com |
Has MS affected your brainstem and cerebellum?People with MS who have lesions in the posterior fossa have a poorer prognosis. However, there are things that can be done for each of the problems tha…
| 42 | 61 | Share this post Has MS affected your brainstem and cerebellum? gavingiovannoni.substack.com |
Amitriptyline: the neurologist's dirty little secretAre you taking amitriptyline? As someone with MS amitriptyline's side effect profile may not be in your best interests.
| 44 | 55 | Share this post Amitriptyline: the neurologist's dirty little secret gavingiovannoni.substack.com |
Case study: rapidly-evolving severe MS and pregnancyThis is a very complex case of someone with recently diagnosed rapidly evolving severe MS with apparent breakthrough activity on natalizumab on a backg…
| 4 | Share this post Case study: rapidly-evolving severe MS and pregnancy gavingiovannoni.substack.com |
The consequences of not treating MSAre there valid reasons not to treat MS with a disease-modifying therapy? What are the consequences of not treating MS? Is watchful waiting justified?
| 44 | 42 | Share this post The consequences of not treating MS gavingiovannoni.substack.com |
Publish on Substack
Prof G's MS-Selfie Newsletter is on Substack – the place for independent writing