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How to avoid a DMT cul-de-sac?
You should try to push back from being labelled as having SPMS or PPMS to prevent limiting your treatment options.
7 hrs ago
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Gavin Giovannoni
8
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How to avoid a DMT cul-de-sac?
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30
Q&A 99: treatment sequencing
An anti-CD20 therapy or cladribine? Or should I wait for tolebrutinib to become available?
Jul 7
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Gavin Giovannoni
15
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Q&A 99: treatment sequencing
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51
Q&A 98: male sexual dysfunction in MS
Sexual dysfunction is a common symptom in men with MS, with a prevalence that surpasses that seen in the general population and other chronic disease…
Jul 1
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Gavin Giovannoni
6
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Q&A 98: male sexual dysfunction in MS
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4
June 2025
Gamechangers
I predict that cheap generic oral cladribine, fenebrutinib, prophylactic EBV vaccines and antiviral treatments for acute EBV-associated infectious…
Jun 30
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Gavin Giovannoni
22
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Gamechangers
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53
O Canada
When you get away from the toads, you have time to test new ideas and revisit old ideas and concepts with a critical audience.
Jun 25
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Gavin Giovannoni
13
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16:51
Q&A 97: Chemobrain?
The chemotherapy you had for your ovarian cancer (cisplatin and taxol) are neurotoxic and are likely to have contributed to your worsening function.
Jun 24
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Gavin Giovannoni
5
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Q&A 97: Chemobrain?
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Q&A 96: skin rejuvenation therapy and MS
Is it safe for someone with MS to have polynucleotide skin injections and radio frequency, ultrasound and micro-needling therapy for skin rejuvenation?
Jun 18
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Gavin Giovannoni
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Q&A 96: skin rejuvenation therapy and MS
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Q&A 95: I live in Scotland should I have AHSCT done privately?
Almost all the cases of MS treated with AHSCT in the UK as being performed in London and Sheffield, the epicentres of AHSCT MS treatment.
Jun 16
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Gavin Giovannoni
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Q&A 95: I live in Scotland should I have AHSCT done privately?
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Q&A 94: rebound on switching from fingolimod to cladribine
I don’t think cladribine has failed you. Sadly, your relapse occurred in a window before cladribine had a chance to work. This was preventable.
Jun 12
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Gavin Giovannoni
9
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Q&A 94: rebound on switching from fingolimod to cladribine
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16
Type 1 diabetes prevention: lessons for MS
As a thought experiment would you trade in MS for having T1DM or would you stick with the autoimmune disease you know already?
Jun 10
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Gavin Giovannoni
7
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Type 1 diabetes prevention: lessons for MS
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25
An NHS in crisis
The UK public requires a new deal with the NHS, becoming a safety net and not necessarily the sole healthcare provider for its citizens.
Jun 9
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Gavin Giovannoni
12
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An NHS in crisis
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40
Infectious mononucleosis - a pragmatic target for preventing multiple sclerosis
EBV vaccines & antiviral treatment of IM
Jun 6
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Gavin Giovannoni
18
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Infectious mononucleosis - a pragmatic target for preventing multiple sclerosis
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