Questions
I was hoping you could answer a question regarding taking a daily preventative dose of 400mg once daily aciclovir for repeated bouts of HSV1 on the palate and gums. Since starting ocrelizumab (Ocrevus), I have had six bouts in approximately 7-8 months with no known trigger apart from the first, which was shortly after my COVID-19 and flu vaccines. This was my worst outbreak. I had never been aware of having herpes before starting ocrelizumab treatment. I had never had a cold sore as far as I was aware, and I also haven’t had them on my lips.
I also have an altered sensation in my face- mainly prickling, which started ten days before the first marked eruption on my left palate- the sensation is worse on the left side of my face - cheek, corner of my lip and part of my chin. I have since had HSV1 on my right palate three times and on the gums and buccally twice. I have had an MRI to rule out a brainstem lesion.
Is there a chance aciclovir, which is used to treat EBV, would help with my MS and prevent HSV1? I was also hopeful it might reduce the sensations in my face. I have been offered amitriptyline for this. However, I am reluctant as it will only mask my symptoms and not treat the cause. My GP has given me the option to take it.
Do the risks of taking a daily antiviral outweigh the benefits, or vice versa? My consultant is happy for my GP to prescribe it, so I would like to know your thoughts.
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Answers
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