MS-Selfie

MS-Selfie

Home
Notes
MS-Selfie Research
MS-Selfie Microsite
Contact
Q&A
Archive
Leaderboard
About
Getting worse
This newsletter explains why people with MS get worse despite having no evident inflammatory disease activity
 • 
Gavin Giovannoni
46
How to interpret a urine dipstick result
I have written an earlier Newsletter on the use of home dipstick monitoring for the early detection of urinary tract infections (UTIs). This is a…
 • 
Gavin Giovannoni
17
13:10
Q&A 61: anaesthesia and MS
It is crucial to look out for complications and have a contact number and a plan to manage these complications if the need arises.
 • 
Gavin Giovannoni
22
Q&A 15 - MS-Selfie
How come my limbs that work are weak but much stronger when I yawn? When the nerve fibres are destroyed, growing new myelin -if possible- won't help…
 • 
Gavin Giovannoni
8
Q&A 16 - MS-Selfie
I cannot ejaculate; what can I do? AHSCT has failed me; should I start teriflunomide or leflunomide? As a male will teriflunomide cause harm to my…
 • 
Gavin Giovannoni
8
Q&A 72: Smouldering MS: siponimod or cladribine?
If tolebrutinib were licensed, this patient would be an ideal candidate to be switched to this treatment.
 • 
Gavin Giovannoni
34
Should I switch from ocrelizumab to ofatumumab?
Is ofatumumab safer than ocrelizumab? Ofatumumab scores higher than ocrelizumab on relapses. Does this mean it is also more effective?
 • 
Gavin Giovannoni
70
19:29
Q&A 17 - beyond no evident inflammatory disease activity or NEIDA
What should the future treatment target be for people with MS? Is it possible to have a blood neurofilament level done? Will measuring spinal fluid…
 • 
Gavin Giovannoni
15
12:33
Spring COVID-19 Update
A change in philosophy is telling us that public health officials are currently playing the endgame of the COVID-19 pandemic. This in itself must be…
 • 
Gavin Giovannoni
36
14:27
Q&A 59: Will tolebrutinib change the willingness of neurologists to diagnose smouldering MS?
He told me to forget about smouldering MS and that I also don’t have secondary progressive MS. He told me to carry on as best I can. Am I going mad?
 • 
Gavin Giovannoni
32
MS-SELFIE LIVE Q&A-1
A recording from Gavin Giovannoni's live video
 • 
Gavin Giovannoni
35
41:52
Amitriptyline: the neurologist's dirty little secret
Are you taking amitriptyline? As someone with MS amitriptyline's side effect profile may not be in your best interests.
 • 
Gavin Giovannoni
66
© 2025 Gavin Giovannoni
Privacy ∙ Terms ∙ Collection notice
Start writingGet the app
Substack is the home for great culture