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Q&A 92: shingles on ocrelizumab
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Q&A 92: shingles on ocrelizumab

Is shingles a common complication of ocrelizumab treatment?
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Case study

I am 35 years old and have relapsing MS. I have been stable on ocrelizumab for the last three and a half years. I have just developed shingles, which is a very unpleasant rash across the left side of my chest onto my breast. I have an intense burning and prickling sensation where the rash is. Is shingles a common complication of ocrelizumab treatment? My pharmacist has given me acyclovir. Is this appropriate? Why wasn’t I offered the Shingrix vaccine before I started ocrelizumab? What about antiviral prophylaxis?

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Prof G’s answers

Q: Is shingles a common complication of ocrelizumab treatment?

Yes, ……

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