11 Comments
Sep 23, 2021Liked by Gavin Giovannoni

A couple of questions Prof.....at the start of the vaccination period your advice was that some immunity was better than none. For a number of ocrelizumab patients, by the time they wait for b-cell repopulation we will be in to next Spring and the winter wave will have hopefully passed. Should these patients grab the chance to boost t-cell responses or not bother? Also, the flu jab invites are beginning to come out. Again, i assume the advice would be to take up this offer but will it really help with no bcells?

Expand full comment
Sep 23, 2021Liked by Gavin Giovannoni

This is really helpful. I'm in a similar position in terms of vaccination dates and ocrevus schedules, though a little older at 40. I haven't had an antibody test though, so should probably seek one out.

Expand full comment

Hi Prof, would this apply to someone like me who has been on rituximab for 4 1/2 years last infusion 18 months ago delayed due to multiple shingles infections. I have now had all my necessary booster vaccinations including Shingrix. Am I correct in thinking that we would also recommend that if possible I should have Moderna as first choice booster 3 if not possible then Pfizer.

Expand full comment

Thanks for sharing this case study Prof G, it's reassuring to read as the lady and myself are a similar-ish age/weight/Ocrevus/antibody response.. roll on the next vaccine..

Expand full comment

I’m 61…. I have delayed, possibly stopped, my infusion of orcrelizumab. Am talking to neurologist on 6/10. I feel the risk of Covid greater than the risk of a relapse… and tbh…maybe I shouldn’t be on it anyway? I can’t stay locked away, I have young grandchildren and I want to enjoy them. Time for a re-think.

Expand full comment

There is a box for neurological disease including MS. No mention of dmt.

Expand full comment