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Uncertainty associated with MS: are you comfortable with it?
Is uncertainty a problem for you? Is this study’s findings consistent with your experiences? What do we do with this information?
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Gavin Giovannoni
66

February 2024

Will CD19-targeted CAR T-cell therapy cure MS?
Who is right; the naysayers saying CAR T-cells are too risky, or those of us who want to press ahead with CD-19-targeted CAR T-cell therapies in MS?
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Gavin Giovannoni
42
Will Frexalimab replace the anti-CD20s?
It is clear to me, and it should be clear to my colleagues, that anti-CD20 therapies have a limited shelf-life as a treatment for MS and will not be the…
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Gavin Giovannoni
48
12:01
Hyper-targeted T-cell therapies
What can we learn from treating other autoimmune diseases? Will we be able to prove that MS is an antigen-specific T-cell mediated autoimmune disease?
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Gavin Giovannoni
22

January 2024

Worsening MS post-COVID
So many people with MS who have had COVID-19 have said that COVID-19 has made their MS worse. Do you relate to this?
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Gavin Giovannoni
79

December 2023

Should I take anti-retroviral drugs to treat my MS?
... I know that many of you are taking HAART based on hope. Let me remind you that ‘hope is not a strategy to treat MS’.
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Gavin Giovannoni
46
AHSCT vs. CAR T-cells to treat MS
Do we have to use AHSCT an immunological sledgehammer to treat MS? Can't we use something simpler like a targeted immunotherapy or an antiviral to…
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Gavin Giovannoni
77
20:47

November 2023

Atara Bio's EMBOLD study is negative
What does this mean for the EBV hypothesis of MS?
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Gavin Giovannoni
26

October 2023

September 2023

Immune tolerance in multiple sclerosis: the holy grail or not?
Research news - how important are papers describing new auto-antibodies in people with MS and new ways of inducing immune tolerance to auto-antigens?
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Gavin Giovannoni
20

August 2023

To cure or not to cure MS, that is the question
The billion-dollar question: Did early treatment with oral cladribine cure most of these subjects with CIS?
 • 
Gavin Giovannoni
59
19:19

July 2023

What has a scrubbing brush got to do with multiple sclerosis?
Can we scrub the brain and spinal cord clean of B-cells and plasma cells to treat smouldering MS? Treating beyond NEIDA (no evident inflammatory disease…
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Gavin Giovannoni
39
14:36
© 2024 Gavin Giovannoni
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